National Canine Research Council, the Wisdom Panel test was found to be 84% accurate when dogs were tested that had two purebred parents. With the addition of more genetic markers to the test, the test is believed to be 90% accurate. This simply means that the DNA provided will have a 90% accuracy in matching the Genetic Markers that are stored in that companies database.
There is also the chance of human error while collecting the sample, delivery of the sample and the actual testing of the sample. Human error at this point is an unknown percent of inaccuracy.
During the development of Wisdom Panel over 19 million genetic markers were analyzed, with over 13,000 dogs evaluated for the Wisdom Panel. However 13,000 dogs is about .01625% of the 80 million dogs owned in the United States.
“Wisdom Panel dog DNA tests aren’t designed or intended to determine or validate whether a dog is purebred. Rather, they’re meant to demonstrate how closely a dog matches the reference genetic signature for a breed.” This is pulled directly from Wisdom Panel’s Website.
“Embark’s reference database of tens of thousands of purebred dogs is the largest and most diverse in the world.” This is pulled directly from the Embark’s Website. Even if they have 100,000 Purebred Dog Samples, that’s only .125% of all the dogs currently living in the United States.
“For a variety of reasons, the registered purebred dog tested by Embark may not perfectly match the genetic signature of the reference panel. ” This is pulled directly from Embark’s Website.
Gene Mutations and Recombination that can happen in the same litter of puppies will give litter mates that are Purebreds different results.
Genetic drift and Selection will also play a role when DNA Testing puppies with two Purebred Parents. These can show different DNA results in one generation of puppies.
Finding single-gene mutations for whether a dog acquires a disease or health condition while doing a DNA Test is a “lousy predictor” says Dr.Moses and two other Boston-based animal research experts.
Regulation for the Dog DNA Industry is basically non existent, and doesn’t even come close to the regulation of Human DNA Industry. The FDA does not regulate the Dog DNA industry.
Wisdom Panel says – “Wisdom Health’s testing procedures are designed to provide reliable and accurate results, but are not guaranteed.”
DNA My Dog says “The comparison database is really the key to the whole process. During the comparison process, the results for the DNA markers from your mixed breed dog are compared with DNA marker information from thousands and thousands of pure bred dogs.” They claim they are matching against thousands of Purebred Dogs. There is over 80 Million dogs in the United States alone. This is not enough of a sampling to give concrete results.